Apoptosis Signaling Laboratory
Adjunktus: Dr. Sarang Zsolt, Dr. Köröskényi Krisztina
Tanársegéd: Dr. Garabuczi Éva, Kiss Beáta
Ph.D hallgató: Budai Zsófia, Sághy Tibor, Odono A. Eze, Nour Al Zayed, Saravanabhavan Shanmuga Sundar
Laboratóriumi asszisztens: Szegediné Szilágyi Piroska
Leírás
Biokémiai és Molekuláris Biológiai Intézet
Debreceni Egyetem
Egyetem tér 1
H-4010 Debrecen
FAX: +36 52 314-989
Név: Dr. Szondy Zsuzsanna
E-Mail: szondy@med.unideb.hu
Telefon: +36 52 416-432 -64134
Név: Dr. Köröskényi Krisztina Dr. Garabuczi Éva Dr. Sarang Zsolt
E-Mail: kkriszti@med.unideb.hu gevi@med.unideb.hu sarang@med.unideb.hu
Szobaszám: 3.110
Telefon: +36 52 416-432 -64789
Név: Kiss Beáta, Budai Zsófia, Sághy Tibor,
E-Mail: kissbea@med.unideb.hu, budai.zsofia@med.unideb.hu, saghy91@gmail.com
Név: Odono A. Eze, Nour Al Zayed, Saravanabhavan Shanmuga Sundar
Név: Szegediné Szilágyi Piroska,
Szobaszám: 4.047-048
Telefon: +36 52 416-432 -65899
GENERAL INFORMATIONS
RESEARCH TOPICS
12 selected publications
Kiss I, Oskolas H, Toth R, Bouillet P, Toth K, Fulop A, Scholtz B, Ledent C, Fesus L, Szondy Z. Adenosine A2A receptor-mediated cell death of mouse thymocytes involves adenylate cyclase and Bim and is negatively regulated by Nur77. Eur J Immunol. 2006 Jun;36(6):1559-71.
Szondy Z, Mastroberardino PG, Varadi J, Farrace MG, Nagy N, Bak I, Viti I, Wieckowski MR, Melino G, Rizzuto R, Tosaki A, Fesus L, Piacentini M. Tissue transglutaminase (TG2) protects cardiomyocytes against ischemia/reperfusion injury by regulating ATP synthesis. Cell Death Differ. 2006 Oct;13(10):1827-9. Epub 2006 Mar 10.
Sarang Z, Molnar P, Nemeth T, Gomba S, Kardon T, Melino G, Cotecchia S, Fesus L, Szondy Z. Tissue transglutaminase (TG2) acting as G protein protects hepatocytes against Fas-mediated cell death in mice. Hepatology. 2005 Sep;42(3):578-87.
Fesus L, Szondy Z. Transglutaminase 2 in the balance of cell death and survival. FEBS Lett. 2005 Jun 13;579(15):3297-302. Epub 2005 Apr 7. Review.
Ludanyi K, Nagy ZS, Alexa M, Reichert U, Michel S, Fesus L, Szondy Z. Ligation of RARgamma inhibits proliferation of phytohaemagglutinin-stimulated T-cells via down-regulating JAK3 protein levels. Immunol Lett. 2005 Apr 15;98(1):103-13. Epub 2004 Nov 24.
Toth B, Ludanyi K, Kiss I, Reichert U, Michel S, Fesus L, Szondy Z. Retinoids induce Fas(CD95) ligand cell surface expression via RARgamma and nur77 in T cells. Eur J Immunol. 2004 Mar;34(3):827-36.
Szondy Z, Sarang Z, Molnar P, Nemeth T, Piacentini M, Mastroberardino PG, Falasca L, Aeschlimann D, Kovacs J, Kiss I, Szegezdi E, Lakos G, Rajnavolgyi E, Birckbichler PJ, Melino G, Fesus L. Transglutaminase 2-/- mice reveal a phagocytosis-associated crosstalk between macrophages and apoptotic cells. Proc Natl Acad Sci U S A. 2003 Jun 24;100(13):7812-7. Epub 2003 Jun 16.
Szegezdi E, Kiss I, Simon A, Blasko B, Reichert U, Michel S, Sandor M, Fesus L, Szondy Z. Ligation of retinoic acid receptor alpha regulates negative selection of thymocytes by inhibiting both DNA binding of nur77 and synthesis of bim. J Immunol. 2003 Apr 1;170(7):3577-84.
Korponay-Szabo IR, Laurila K, Szondy Z, Halttunen T, Szalai Z, Dahlbom I, Rantala I, Kovacs JB, Fesus L, Maki M. Missing endomysial and reticulin binding of coeliac antibodies in transglutaminase 2 knockout tissues. Gut. 2003 Feb;52(2):199-204.
Amendola A, Fesus L, Piacentini M, Szondy Z. "Tissue" transglutaminase in AIDS. J Immunol Methods. 2002 Jul 1;265(1-2):145-59. Review.
Szondy Z, Toth R, Szegezdi E, Reichert U, Ancian P, Fesus L. Cell death in HIV pathogenesis and its modulation by retinoids. Ann N Y Acad Sci. 2001 Nov;946:95-107. Review.
Toth R, Szegezdi E, Reichert U, Bernardon JM, Michel S, Ancian P, Kis-Toth K, Macsari Z, Fesus L, Szondy Z. Activation-induced apoptosis and cell surface expression of Fas (CD95) ligand are reciprocally regulated by retinoic acid receptor alpha and gamma and involve nur77 in T cells. Eur J Immunol. 2001 May;31(5):1382-91.