Személyreszabott Orvoslás Kutatócsoport

Dr. Bálint László Bálint


A kutatócsoport honlapja

In cancer, the genome is transformed in such a manner that the uncontrolled cell division and growth of the cancer is destroying the organism itself.

The activity of the genome is controlled by distinct mechanisms on the chromatin level by determining the boundaries of active and inactive regions.

Components of these regulatory processes are the super-enhancers, or clustered enhancers with their transcription factors and the protein complexes that determine the boundaries of chromatin domains.

The changes in cell identity can be identified both on genotype and phenotype levels and their initial phase is initiated by changes on the chromatin level. We plan to characterize these chromatin level changes of tumour evolution.